DuckCorp Dico

Found one definition

1.                 From The Jargon File (version 4.4.7, 29 Dec 2003):
                   
   
   
                   
                     
   macro-
    pref.
       Large. Opposite of micro-. In the mainstream and among other technical
       cultures (for example, medical people) this competes with the prefix mega-
    , but hackers tend to restrict the latter to quantification.