From The Collaborative International Dictionary of English v.0.48:
Lopsided \Lop"sid`ed\, a. [Lop + side. Cf. Lobsided.] 1. Leaning to one side because of some defect of structure; as, a lopsided ship. --Marryat. [1913 Webster]
2. Unbalanced; poorly proportioned; having much more on one side than the other; -- also used metaphorically; as, a lopsided victory. [1913 Webster +PJC]
3. Full of idiosyncrasies. --J. S. Mill. [1913 Webster]