From The Collaborative International Dictionary of English v.0.48:
Insane \In*sane"\, a. [L. insanus. See In- not, and Sane.] 1. Exhibiting unsoundness or disorder of mind; not sane; mad; deranged in mind; delirious; distracted. See Insanity, 2. [1913 Webster]
2. Used by, or appropriated to, insane persons; as, an insane hospital. [1913 Webster]
3. Causing insanity or madness. [R.] [1913 Webster]
Or have we eaten on the insaneroot That takes the reason prisoner ? --Shak. [1913 Webster]
4. Characterized by insanity or the utmost folly; chimerical; unpractical; as, an insane plan, attempt, etc. [1913 Webster]
I know not which was the insane measure. --Southey. [1913 Webster]